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Superoxide dismutase and cytochrome oxidase activities in light and heavy synaptic mitochondria from rat cerebral cortex during aging

✍ Scribed by A. Vanella; R. F. Villa; A. Gorini; A. Campisi; Prof. A. M. Giuffrida-Stella


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
488 KB
Volume
22
Category
Article
ISSN
0360-4012

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✦ Synopsis


The specific activities of superoxide dismutase (SOD) and cytochrome oxidase (COX) in light and heavy synaptic mitochondria from rat cerebral cortex at different ages (4, 8, 12, 16, 20, and 24 months) have been measured. The specific activity of COX was significantly higher in light synaptic mitochondria than in heavy ones at all ages examined. However, no significant difference during aging was shown. A marked decrease of SOD in light and heavy synaptic mitochondria during aging was observed.