Superoxide dismutase and catalase are transported by endo- and exocytosis from coronary capillaries into myocytes of reperfused dog heart

Exogenous superoxide dismutase and catal

Exogenous superoxide dismutase and catalase promote recovery of function in isolated rat heart after regional ischemia and may be transported from capillaries into myocytes

✍ Joseph R. Koke; Nicolaos J. Christodoulides; Laurie L. Chudej; Neville Bittar 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 634 KB

The effects of infusing superoxide dismutase (SOD) and catalase (CAT) into the coronary circulation were investigated in isolated, working rat hearts prior to and during a 15 minute episode of regional ischemia followed by 30 minutes reperfusion. Aortic output, left ventricular pressure and dP/dT we