✦ LIBER ✦

Supercritical fluid extraction of benzodiazepines in solid dosage forms

✍ Scribed by Julia K. Lawrence; A.Karl Larsen Jr.; Ian R. Tebbett

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 467 KB
Volume: 288
Category: Article
ISSN: 0003-2670
DOI: 10.1016/0003-2670(94)85121-2

No coin nor oath required. For personal study only.

✦ Synopsis

Several benzodiazepines were separated from the matrices of their standard dosage forms using supercritical fluid extraction. Extracts were further processed by gas chromatography-mass spectrometry and/or Fourier transform infrared spectrometry. Extracts of suitable purity and quantity for mass spectral analysis were easily obtainable from even the lowest concentration dosage forms of the drugs tested.

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