𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Supercritical extraction of phloroglucinol and benzophenone derivatives from Hypericum carinatum: Quantification and mathematical modeling

✍ Scribed by Francisco M. C. Barros; Flávia C. Silva; Jéssica M. Nunes; Rubem M. F. Vargas; Eduardo Cassel; Gilsane L. von Poser

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
148 KB
Volume
34
Category
Article
ISSN
1615-9306

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The aerial parts of Hypericum carinatum (Guttiferae) were extracted with supercritical carbon dioxide under constant temperature (40, 50 or 60°C) and gradual pressure increase (90, 120, 150 and 200 bar) aiming at the recovery of enriched fractions containing uliginosin B, cariphenone A and cariphenone B, compounds of pharmaceutical interest. The yields of these substances were determined by high‐performance liquid chromatography and compared with those obtained with n‐hexane maceration. The supercritical‐fluid extraction showed higher selectivity than the conventional solvent extraction method. After defining 40°C and 90 bar as the best conditions to obtain the target compounds, a mathematical model was used for the extraction process and a good correlation was achieved with the experimental data.

📜 SIMILAR VOLUMES

Mathematical Modeling of Supercritical E
Mathematical Modeling of Supercritical Extraction of Valerenic Acid from Valeriana officinalis L.
✍ A. Salimi; S. Fatemi; H. Zakizadeh Nei Nei; A. Safaralie 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 220 KB 👁 1 views

## Abstract The dynamic behavior of supercritical fluid extraction (SFE) of valerenic acid (VA) from valerian (__Valeriana officinalis__ L.) roots was studied by mathematical modeling. The extraction yield of VA was considered as the most desirable compound among the other extracted constituents. A