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Supercoiled plasmid DNA purification by integrating membrane technology with a monolithic chromatography

✍ Scribed by Nunes, Catherine; Sousa, Ângela; Nunes, José C.; Morão, António M.; Sousa, Fani; Queiroz, João A.

Book ID: 124058393
Publisher: John Wiley and Sons
Year: 2014
Tongue: English
Weight: 150 KB
Volume: 37
Category: Article
ISSN: 1615-9306
DOI: 10.1002/jssc.201301160

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## Abstract ## Background It is well known that the success of gene transfer to cells and subsequent expression is strictly affected by the vector manufacturing process. Several challenges encountered in the gene therapy field have emphasized the need for the development of novel platforms that al