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Superantigens initiate cognate CD4+ T cell/ B cell interactions leading to early activation and proliferation of B cells

✍ Scribed by Reem Al-Daccak; Bassam Damaj; Paul H. Naccache; Walid Mourad


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
689 KB
Volume
25
Category
Article
ISSN
0014-2980

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## Abstract B cells are the primary targets of infection for mouse mammary tumor virus (MMTV). However, for productive retroviral infection, T cell stimulation through the virally‐encoded superantigen (SAG) is necessary. It activates B cells and leads to cell division and differentiation. To charac