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Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway

✍ Scribed by Li, Ling-bo; Goleva, Elena; Hall, Clifton F.; Ou, Liang-Shiou; Leung, Donald Y.M.


Book ID
119274704
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
472 KB
Volume
114
Category
Article
ISSN
1097-6825

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## Abstract Stimulation of T cells via the T cell receptor (TCR) activates a number of signaling pathways that are potentially involved in the elicitation of physiological responses, such as the production of cytokines. The extracellular signal‐regulated kinases (ERK) are a group of molecules activ