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Super-high-affinity binding site for [3H]diazepam in the presence of Co2+, Ni2+, Cu2+, OR Zn2+

✍ Scribed by S. Mizuno; N. Ogawa; A. Mori


Publisher
Springer
Year
1982
Tongue
English
Weight
293 KB
Volume
7
Category
Article
ISSN
0364-3190

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## Abstract [^3^H]TCP, an analog of the dissociative anesthetic phencyclidine (PCP), binds with high affinity to two sites in guinea pig brain membranes, one that is MK‐801 sensitive and one that is not. The MK‐801‐sensitive site (PCP site 1) is associated with NMDA receptors, whereas the MK‐801‐in