Hexokinase II gene transfer protects aga
✍
Juan Carlos Corona; Alfredo Gimenez-Cassina; Filip Lim; Javier Díaz-Nido
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 407 KB
## Abstract A typical feature of Parkinson's disease is the progressive loss of dopaminergic neurons in the substantia nigra, in which inhibition of mitochondrial complex I activity may play an important role. Rotenone or 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) inhibit the mitochondrial