✦ LIBER ✦

Sun exposure predicts risk of ocular melanoma in Australia

✍ Scribed by Claire M. Vajdic; Anne Kricker; Michael Giblin; John McKenzie; Joanne Aitken; Graham G. Giles; Bruce K. Armstrong

Publisher: John Wiley and Sons
Year: 2002
Tongue: French
Weight: 104 KB
Volume: 101
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.10579

No coin nor oath required. For personal study only.

✦ Synopsis

Previous studies examining sun exposure and ocular melanoma have produced inconsistent results. We investigated this association in a population-based case-control study in Australia. Cases (n = 290) aged 18-79 years were diagnosed between January 1996 and July 1998. Controls (n = 893) were randomly selected from the electoral rolls and frequency-matched to cases by age, sex and state. A self-administered questionnaire and a telephone interview measured sun exposure on weekdays and weekends at 10, 20, 30 and 40 years of age and over the whole of life for specific jobs and recreations. Multivariate logistic regression models of ocular melanoma and sun exposure contained age, sex, region of birth, eye color and measures of ocular and cutaneous sun sensitivity as covariates. Choroid and ciliary body melanoma (n = 246) was positively associated with time outdoors on weekdays and, less persuasively, total time outdoors but not ambient solar irradiance. Odds ratios increased with increasing exposure to OR 1.8 (95% confidence interval 1.1-2.8) for the highest quarter of sun exposure on weekdays up to 40 years of age for men and women together. The strongest positive associations were for total exposure up to 40 years of age, lifetime occupational exposure and total exposure at about 20 years of age in men; all had odds ratios between 2 and 3 in the highest exposure categories. There was inconclusive evidence for an association between sun exposure and iris (n = 25) or conjunctival (n = 19) melanomas. Sun exposure is an independent risk factor for choroidal and ciliary body melanoma in Australia.

📜 SIMILAR VOLUMES

Eye color and cutaneous nevi predict ris

Eye color and cutaneous nevi predict risk of ocular melanoma in Australia

✍ Claire M. Vajdic; Anne Kricker; Michael Giblin; John McKenzie; Joanne Aitken; Gr 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 72 KB

Ethnicity, cutaneous nevi and eye color are generally accepted risk factors for melanoma of the eye, although case-control studies have produced conflicting results. We sought to determine the constitutional risk factors for melanomas of the choroid, ciliary body, iris and conjunctiva in Australia.

Sun exposure and interaction with family

Sun exposure and interaction with family history in risk of melanoma, Queensland, Australia

✍ Victor Siskind; Joanne Aitken; Adèle Green; Nicholas Martin 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 66 KB

## Abstract Sun exposure is the main environmental risk factor for melanoma, but the timing of exposure during life that confers increased risk is controversial. Here we provide the first report of the association between lifetime and age‐specific cumulative ultraviolet exposure and cutaneous melan

Incidence of ocular melanoma in Australi

Incidence of ocular melanoma in Australia from 1990 to 1998

✍ Claire M. Vajdic; Anne Kricker; Michael Giblin; John McKenzie; Joanne Aitken; Gr 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 93 KB

## Abstract Routinely collected incidence data have often lacked specific identification of ocular melanoma in the past and with increasing diagnosis and management of this disease by noninvasive techniques may now underestimate the true incidence. We attempted to accurately measure the incidence o

Influence of sun exposures during childh

Influence of sun exposures during childhood and during adulthood on melanoma risk

✍ Philippe Autier; Jean-François Doré for Epimel; Eortc Melanoma Cooperative Group 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 73 KB

Sun exposure in both childhood and adult life represents the main environmental risk determinant for cutaneous melanoma. However, little is known about the joint effects of sun exposure during early and later life on melanoma risk. A case-control study in Belgium, Germany and France conducted in 199

Biologic markers of sun exposure and mel

Biologic markers of sun exposure and melanoma risk in women: Pooled case–control analysis

✍ Catherine M. Olsen; Michael S. Zens; Adele C. Green; Therese A. Stukel; C. D'Arc 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 155 KB 👁 1 views

## Abstract A model has been proposed whereby melanomas arise through two distinct pathways dependent on the relative influence of host susceptibility and sun exposure. Such pathways may explain site‐specific patterns of melanoma occurrence. To explore this model, we investigated the relationship b

Site-specific risk of cutaneous malignan

Site-specific risk of cutaneous malignant melanoma and pattern of Sun exposure in New Zealand

✍ Jean-Luc Bulliard 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 93 KB 👁 1 views

The site-specific relationship between melanoma and sun exposure was investigated in the high-risk region of New Zealand. Age and latitude of residence were used as biological and geographical proxy measures of exposure for the 16,117 newly incident cases and 3,150 death records reported between 196