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Sumoylation regulates nuclear localization and function of zinc finger transcription factor ZIC3

โœ Scribed by Chen, Li; Ma, Yanlin; Qian, Ling; Wang, Jun


Book ID
120580856
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
586 KB
Volume
1833
Category
Article
ISSN
0167-4889

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## Abstract The transcription factors Sp1, Sp3, and Egrโ€1 bind with their zinc finger DNAโ€binding domains to GCโ€rich sequences in the regulatory regions of their target genes. The similarity of the DNAโ€binding sites of Sp1, Sp3, and Egrโ€1 has triggered the hypothesis that they compete for the same