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SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors

✍ Scribed by Ying Xu; Jie Li; Yong Zuo; Jiong Deng; Li-Shun Wang; Guo-Qiang Chen


Book ID
116335677
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
733 KB
Volume
309
Category
Article
ISSN
0304-3835

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## Abstract Human colon cancer cell lines express epidermal growth factor (EGF) mRNA, secrete EGF and may respond to it __via__ the cell‐surface EGF receptor (EGFR). Expression of these molecules in human colon and colon tumor, however, is not clear. Reverse transcription‐polymerase chain reaction