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Sulphation of (−)-salbutamol in the human liver and duodenum: Interindividual variability

✍ Scribed by G.M. Pacifici; B. Giulianetti; M. Quilici; L. Giuliani; R. Spisni; M. Nervi

Book ID
119179488
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
135 KB
Volume
31
Category
Article
ISSN
1043-6618

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Interindividual variability in the rate
Interindividual variability in the rate of salbutamol sulphation in the human lung
✍ G. M. Pacifici; C. Santi; A. Mussi; C. A. Ageletti 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 454 KB

The beta2-adrenergic agonist salbutamol is administered by inhalation to treat lung-obstructive disease. Salbutamol is metabolized by conjugation with sulphate, and the sulphation of salbutamol was investigated in human lung. Specimens of lung were obtained at lobectomy from 11 non-smokers, 39 smoke