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Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled

✍ Scribed by Ho-Jin Lee; Nick X. Wang; De-Li Shi; Jie J. Zheng


Book ID
102730534
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
531 KB
Volume
48
Category
Article
ISSN
0044-8249

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## Abstract The cucurbitacins are tetracyclic triterpenes found in plants of the family Cucurbitaceae. Cucurbitacins have been shown to have anti‐cancer and anti‐inflamatory activities. We investigated the anti‐cancer activity of cucurbitacin B extracted from Thai medicinal plant __Trichosanthes cu