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Sulfur mustard induces differentiation in human primary keratinocytes: Opposite roles of p38 and ERK1/2 MAPK

โœ Scribed by Tanja Popp; Virginia Egea; Kai Kehe; Dirk Steinritz; Annette Schmidt; Marianne Jochum; Christian Ries


Book ID
116923809
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
926 KB
Volume
204
Category
Article
ISSN
0378-4274

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## Abstract STI571 is a specific tyrosine kinase inhibitor of Abl kinase. It was previously reported that STI571 induced hemoglobin synthesis in the chronic myelogenous leukemia (CML) cell line K562. However, its mechanisms remain unknown. In this study, we demonstrated that STI571 induced the phos