Enamides 10, upon treatment with Bu 3 SnH-AIBN, gave 5-exo aryl radical cyclization products 11, which were partially desulfurized to give 1-substituted dihydroisoindoles 7 and 12. This method was applied to the synthesis of a model compound 4 of mappicine ketone (1).
โฆ LIBER โฆ
Sulfur-directed 5-Exo selective aryl radical cyclization onto enamide: A simple route to chilenine
โ Scribed by Hiroyuki Ishibashi; Hirotaka Kawanami; Hiroko Iriyama; Masazumi Ikeda
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 250 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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