Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells
β Scribed by Woo Young Choi; Byung Tae Choi; Won Ho Lee; Yung Hyun Choi
- Book ID
- 116313950
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 953 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0753-3322
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Screening of various natural products in a search for novel inducers of apoptosis in human leukemia cells led us to identify the strong apoptosisβinducing activity in a fraction extracted with methanol from the roots of __Sophora subprostrata__ Chun et T. Chen. We purified the compound
Previous studies revealed that polydatin, a natural small compound, possessed protective effect against ischemia/reperfusion injury and inflammation. However, the action and molecular mechanism of its potent anti-cancer activity remain poorly understood. In the present study, polydatin significantly