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Sulfonylureas induce cholesterol accumulation in cultured human intimal cells and macrophages

✍ Scribed by I.A. Sobenin; M.A. Maksumova; E.S. Slavina; M.I. Balabolkin; A.N. Orekhov


Book ID
118324569
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
497 KB
Volume
105
Category
Article
ISSN
0021-9150

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## Abstract Activated T lymphocytes release vesicles, termed exosomes, enriched in cholesterol and exposing phosphatidylserine (PS) at their outer membrane leaflet. Although CD4+ activated T lymphocytes infiltrate an atherosclerotic plaque, the effects of T cell exosomes on the atheroma‐associated