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Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

✍ Scribed by Sanae Kanno, Seishiro Hirano, Morihisa Sagi, Shoetsu Chiba…

Book ID
120747698
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
968 KB
Volume
87
Category
Article
ISSN
0340-5761

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Methylglyoxal (MG) is a physiological metabolite, but it is known to be toxic, inducing stress in cells and causing apoptosis. This study examines molecular mechanisms in the MG-induced signal transduction leading to apoptosis, focusing particularly on the role of JNK activation. We first confirmed