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Sulfatroxazole: pharmacokinetics, metabolism and urinary excretion in goats and pigs

✍ Scribed by L. D. B. KINABO; POUL NIELSEN

Book ID
114744377
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
393 KB
Volume
9
Category
Article
ISSN
0140-7783

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πŸ“œ SIMILAR VOLUMES

Pharmacokinetics, metabolism and renal e
Pharmacokinetics, metabolism and renal excretion of sulfatroxazole and its 5-hydroxy- and N4-acetylmetabolites in man
✍ T. B. Vree; T. B. Vree; Y. A. Hekster; M. W. Tijhuis; E. F. S. Termond; J. F. M. πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 535 KB

Hydroxylation is the predominant pathway of metabolism for sulfatroxazole in the body, accounting for 70 per cent of the dose. Fifteen per cent of the dose is acetylated unimodally and 10 per cent is excreted unchanged. The half-lives of sulfatroxazole and its metabolites 5-hydroxysulfatroxazole and