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Sulfate and methyldopa metabolism: Metabolite patterns and platelet phenol sulfotransferase activity

โœ Scribed by Campbell, Norman R C; Sundaram, Rajah S; Werness, Peter G; Van Loon, Jon; Weinshilboum, Richard M


Book ID
109843790
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
628 KB
Volume
37
Category
Article
ISSN
0009-9236

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Sulfate conjugation is an important pathway in the biotransformation of drugs and neurotransmitters. The thermolabile (TL) form of the enyzme phenol sulfotransferase (PST) catalyzes the sulfation of catecholamine neurotransmitters and drugs such as methyldopa and acetaminophen. Platelet TL PST activ