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Successful use of a plant gene in the treatment of cancer in vivo

✍ Scribed by Cortés, M L; de Felipe, P; Martín, V; Hughes, M A; Izquierdo, M


Book ID
110038297
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
249 KB
Volume
5
Category
Article
ISSN
0969-7128

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Crigler-Najjar type 1 disease (CN1) is a rare inherited metabolic disease characterized by complete absence of hepatic UDP-glucuronosyl transferase (UGT1), resulting in high levels of unconjugated bilirubin. CN1 is an attractive candidate disease for gene therapy. Here we show that in vivo neonatal