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Successful treatment of active Crohn's disease with oral dehydroepiandrosterone (DHEA): An open controlled pilot trial

✍ Scribed by Andus, Tilo; Klebl, Frank; Rogler, Gerhard; Bregenzer, Nicole; Schoelmerich, Juergen; Straub, Rainer H.


Book ID
124147251
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Background: Interleukin-12 (il-12) and interleukin-23 (il-23) are inflammatory cytokines linked to the th-1 and th-17 phenotypes associated with crohn's disease (cd). we investigated the activity and safety of apilimod mesylate (formerly sta-5326), an oral il-12 and il-23 inhibitor, in patients