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Successful thalamic deep brain stimulation for orthostatic tremor

โœ Scribed by Jorge Guridi; Maria C. Rodriguez-Oroz; Javier Arbizu; Manuel Alegre; Elena Prieto; Ignacio Landecho; Miguel Manrique; Julio Artieda; Jose A. Obeso

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
153 KB
Volume
23
Category
Article
ISSN
0885-3185

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โœฆ Synopsis

Abstract

We report a patient with severe orthostatic tremor (OT) unresponsive to pharmacological treatments that was successfully controlled with thalamic (Vim, ventralis intermedius nucleus) deep brain stimulation (DBS) over a 4โ€year period. Cortical activity associated with the OT revealed by EEG backโ€averaging and fluoroโ€deoxiโ€glucose PET were also suppressed in parallel with tremor arrest. This case suggests that Vimโ€DBS may be a useful therapeutic approach for patients highly disabled by OT. ยฉ 2008 Movement Disorder Society

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