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Successful prolonged use of recombinant human insulin-like growth factor-1 in a child with cystic fibrosis

✍ Scribed by Mark E. Haupt; Ellen E. Kim; Adrienne L. Prestridge

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 202 KB
Volume: 46
Category: Article
ISSN: 8755-6863
DOI: 10.1002/ppul.21478

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✦ Synopsis

Abstract

Growth failure is a common and complicated process in children with cystic fibrosis (CF). Growth hormone, which is becoming a more commonly used agent in such patients, has demonstrated beneficial effects aside from increased growth velocity. Recently, insulin‐like growth factor‐1 has gained significant attention in the understanding of growth failure in children with CF. We report the successful prolonged use of recombinant human insulin‐like growth factor‐1 in an adolescent boy with CF, who demonstrated significant clinical benefits from the therapy. Pediatr. Pulmonol. 2011; 46:1137–1141. © 2011 Wiley Periodicals, Inc.

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