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Successful preparation and specificity studies of monoclonal antibodies against lung adenocarcinoma

Book ID
122550605
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
94 KB
Volume
2
Category
Article
ISSN
0169-5002

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Monoclonal antibodies against mesothelia
Monoclonal antibodies against mesothelial membrane antigen discriminate between malignant mesothelioma and lung adenocarcinoma
โœ Rolf A. Stahel; Carl J. O'Hara; Robert Weibel; Alexander Martin ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 781 KB

Monoclonal antibodies (MAbs) were generated by immunizing mice with the mesothelioma cell line SPC111 and selected by indirect immunofluorescence on viable cells. Indirect immunofluorescence staining and radioimmunoassays demonstrated selective binding of the antibodies ME1 and ME2 with the surface