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Successful In Vitro Priming of EBV-Specific CD8+ T Cells Endowed with Strong Cytotoxic Function from T Cells of EBV-Seronegative Children

✍ Scribed by P. Comoli; F. Ginevri; R. Maccario; C. Frasson; U. Valente; S. Basso; M. Labirio; G.-C. Huang; E. Verrina; F. Baldanti; F. Perfumo; F. Locatelli

Book ID: 114804008
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 285 KB
Volume: 6
Category: Article
ISSN: 1600-6135
DOI: 10.1111/j.1600-6143.2006.01429.x

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## BACKGROUND. Most strategies in cancer immunotherapy are aimed at the induction of a strong cellular immune response against the tumor. Particularly, CD8 + T lymphocytes have been proven in multiple animal models to be critical for the eradication of solid tumors. METHODS. We used a population o