Successful hepatitis B reinfection prophylaxis with lamivudine and hepatitis B immune globulin in patients with positive HBV-DNA at time of liver transplantation
โ Scribed by J. Rosenau; H.L. Tillmann; M.J. Bahr; C. Trautwein; K.H.W. Boeker; B. Nashan; J. Klempnauer; M.P. Manns
- Book ID
- 117231509
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 41 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0041-1345
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## Abstract Recurrent hepatitis B virus (HBV) infection after liver transplantation can be prevented by prophylactic hepatitis B immune globulin (HBIG) and lamivudine therapy. However, reinfection may still occur due to the emergence of immune escape mutants and mutants of the YMDD motif. The full
Current protocols for prophylaxis against allograft reinfection after liver transplantation for chronic hepatitis B virus (HBV) infection include the administration of large doses of hepatitis B immune globulin (HBIG), with considerable associated economic costs. Monotherapeutic prophylaxis with lam