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Subunit Dependence of Na Channel Slow Inactivation and Open Channel Block in Cerebellar Neurons

✍ Scribed by Aman, Teresa K.; Raman, Indira M.


Book ID
119920681
Publisher
Biophysical Society
Year
2007
Tongue
English
Weight
787 KB
Volume
92
Category
Article
ISSN
0006-3495

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Whole-cell patch-clamp experiments were performed with neurons cultured from rat dorsal root ganglia (DRG). Two types of Na+ currents were identified on the basis of sensitivity to tetrodotoxin. One type was blocked by 0.1 nM tetrodotoxin, while the other type was insensitive to 10 microM tetrodotox