𝔖 Bobbio Scriptorium
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Substructure searching of heterocycles by computer generation of potential aliphatic precursors

✍ Scribed by Synge, Richard L. M.


Book ID
126107011
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
618 KB
Volume
25
Category
Article
ISSN
0095-2338

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Structurally novel potential dopamine agonists were designed by searching databases of 3D structures to find templates that match geometric criteria and can be modified into molecules suggested for synthesis. A search of 54,296 3D structures from three different databases generated 499 structurally