Novel Peptidyl Aryl Vinyl Sulfones as Hi
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Laura Mendieta; Anna Picó; Teresa Tarragó; Meritxell Teixidó; Marcos Castillo; L
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Article
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2010
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John Wiley and Sons
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English
⚖ 995 KB
## Abstract __Herein we present the design, synthesis, and evaluation of a structurally novel library of 20 peptidyl 3‐aryl vinyl sulfones as inhibitors of cathepsins L and B. The building blocks, described here for the first time, were synthesized in a highly efficient and enantioselective manner,