✦ LIBER ✦
Substrate specificity of the CYC2 enzyme from Kitasatospora griseola: production of sclarene, biformene, and novel bicyclic diterpenes by the enzymatic reactions of labdane- and halimane-type diterpene diphosphates
✍ Scribed by Chiaki Nakano; Tsutomu Hoshino; Tsutomu Sato; Tomonobu Toyomasu; Tohru Dairi; Takeshi Sassa
- Book ID
- 104097114
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 242 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The enzymatic reaction of copalyl diphosphate (CDP), ent-CDP, syn-CDP, and tuberculosinyl diphosphate with the CYC2 enzyme from Kitasatospora griseola afforded sclarene, biformene, and novel diterpenes having a buta-1,3-diene moiety in the side chain. The substrate specificity of the CYC2 is discussed.