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Substrate Specificity of Deubiquitinating Enzymes: Ubiquitin C-Terminal Hydrolases†

✍ Scribed by Larsen, Christopher N.; Krantz, Bryan A.; Wilkinson, Keith D.


Book ID
111870443
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
169 KB
Volume
37
Category
Article
ISSN
0006-2960

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## Abstract Ubiquitin C‐terminal hydrolases (UCHs) comprise a family of deubiquitinating enzymes that play a role in the removal of multi‐ubiquitin chains from proteins that are posttranslationally modified by ubiquitination to be targeted for proteolysis by the 26S proteasome. The UCH‐enzymes also