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Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members

✍ Scribed by Kim, S.-T.; Lim, D.-S.; Canman, C. E.; Kastan, M. B.

Book ID
125541130
Publisher
The American Society for Biochemistry and Molecular Biology
Year
1999
Tongue
English
Weight
711 KB
Volume
274
Category
Article
ISSN
0021-9258

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To ensure signalling fidelity, kinases must act only on a defined subset of cellular targets. Appreciating the basis for this substrate specificity is essential for understanding the role of an individual protein kinase in a particular cellular process. The specificity in the cell is determined by a