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Substrate specific metabolism by polymorphic cytochrome P450 2D6 alleles

✍ Scribed by Alessia Bogni; Mario Monshouwer; Anna Moscone; Mats Hidestrand; Magnus Ingelman-Sundberg; Thomas Hartung; Sandra Coecke

Book ID
116919280
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
185 KB
Volume
19
Category
Article
ISSN
0887-2333

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Objective The sum of the serum levels of risperidone (RIS) and 9-hydroxyrisperidone (9-OH-RIS), which is the active moiety serum level, could be important for estimating the clinical effects of RIS. However, there have been no consistent results reported about the relationship between cytochrome P45