Substrate Shape Determines Specificity of Recognition for HIV-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
โ Scribed by Moses Prabu-Jeyabalan; Ellen Nalivaika; Celia A. Schiffer
- Book ID
- 114329051
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 504 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0969-2126
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The crystal structure of a thermophilic alcohol dehydrogenase (TBAD) from Thermoanaerobacter brockii has been determined in a binary complex with sec-butanol as substrate to a resolution of 3.0 A ห. Van der Waals interactions of the carbon C1 atom of sec-butanol with atoms in His59, Ala85, Trp110, A