In this report the structure-activity relationships of a series of novel (N-acyl-N-alkyl)glycyl borolysine thrombin inhibitors are described. This work culminates in the discovery of (N-3phenylpropanoyl-N-phenethyl)glycyl borolysine (12j), a potent, orally active inhibitor with a binding conformatio
Substrate-related phosphonopeptides, a new class of thrombin inhibitors
✍ Scribed by Leifeng Cheng; Christopher A. Goodwin; Michael F. Scully; Vijay V. Kakkar; Göran Claeson
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 255 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v