The intestinal efflux pump, P-glycoprotein (P-gp), located in the apical membranes of intestinal absorptive cells, can reduce the bioavailability of a wide range of drugs which are substrates for this membrane transporter. In addition to anticancer and anti-HIV drugs, NCEs for other disease indicati
β¦ LIBER β¦
Substrate- and species-dependent inhibition of p-glycoprotein-mediated transport: Implications for predicting in vivo drug interactions
β Scribed by Joseph K. Zolnerciks; Catherine L. Booth-Genthe; Anshul Gupta; Jennifer Harris; Jashvant D. Unadkat
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 138 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0022-3549
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