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Substitution électrophile aromatique dans l'anhydride sulfureux liquide. Etude cinétique de la réaction de bromation d'anisoles monosubstitués. Transmission des effets électroniques et caractéristiques de l'état de transition

✍ Scribed by Paul Castellonèse; Pierre Villa


Publisher
John Wiley and Sons
Year
1983
Tongue
German
Weight
457 KB
Volume
66
Category
Article
ISSN
0018-019X

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✦ Synopsis


Reactivity‐structure correlations for anisole and eleven of its substituted derivatives established from bromination rate constants in liquid SO~2~, unlike observations in water, show the reaction to be highly sensitive to substituent effects, (ρ = −7.1; ρ = −10.51). This result is ascribed to the solvation of the methoxy group which decreases the conjugation of para‐substituted (ρ = −9.70) compared to that of ortho‐substituted derivatives (ρ = −8.86). The highly solvated transition state lies far from reactants on the reaction coordinate and the positive charge developed in this state is nearly unity.