Substitution analog peptide derived from HER-2 can efficiently induce HER-2-specific, HLA-A24 restricted CTLs
β Scribed by Kousaku Mimura; Koji Kono; Scott Southwood; John Fikes; Akihiro Takahashi; Naoto Miyagawa; Hidemitsu Sugai; Hideki Fujii
- Book ID
- 105967047
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 321 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0340-7004
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We have identified an H-2K(d)-binding peptide, HER2p780 (PYVSRLLGI), derived from murine HER2/neu (HER2), that can induce HER2-specific murine cytotoxic T lymphocytes (CTL). Weekly vaccination of BALB/c mice by syngeneic dendritic cells pulsed with HER2p780 peptide, entirely common to murine and hum
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