๐”– Bobbio Scriptorium
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Substituted Xanthines. I. Preparation and Properties of Some Choline Theophyllinates

โœ Scribed by Duesel, B.F. ;Berman, H. ;Schachter, R.J.

Publisher
Elsevier
Year
1954
Weight
378 KB
Volume
43
Category
Article
ISSN
0095-9553

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โœฆ Synopsis

If one considers as favorable properties of an antispasmodic agent a high activity in the various intestinal preparations relative to activity on blood pressure, salivation or lacrimation, the 3-hydroxy piperidines generally appear more desirable than atropine. In the most active derivatives, JB-323 and JB-340, this is evidenced only in the rat, while for the remaining analogs it is, in general, apparent in each intraspecies comparison.

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