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Substituted Quinazolines. Part 2. Synthesis and in-vitro Anticancer Evaluation of New 2-Substituted Mercapto-3H-quinazoline Analogues.

✍ Scribed by Ashraf A. Khalil; Sami G. Abdel Hamide; Abdulrahman M. Al-Obaid; Hussein I. El-Subbagh


Publisher
John Wiley and Sons
Year
2003
Weight
116 KB
Volume
34
Category
Article
ISSN
0931-7597

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Substituted Quinazolines, Part 2. Synthe
✍ Ashraf A. Khalil; Sami G. Abdel Hamide; Abdulrahman M. Al-Obaid; Hussein I. El-S πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 170 KB πŸ‘ 2 views

## Abstract A new series of 2‐substituted mercapto‐3__H__‐quinozolines bearing 6‐iodo and 2‐heteroarylthio functions was synthesized and screened for their in vitro antitumor activity. Eighteen compounds were identified as active anticancer agents. __N__′‐[(3‐Benzyl‐4‐oxo‐6‐iodo‐3__H__‐quinazoline‐