Substituted 2-amino-1,3,4-thiadiazines: a novel solid-phase approach
β Scribed by John Paul Kilburn; Jesper Lau; Raymond C.F. Jones
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 66 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The first solid-phase synthesis of 2-substituted-3-(substituted sulfanyl)-1,2,4-benzothiadiazine 1,1-dioxides has been developed. Synthesis of the title compounds was achieved as follows: (1) sulfonylation of solid-supported primary amines with 2-nitrobenzenesulfonylchlorides, (2) reduction of the n
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