Substituierte N,N′-Bis(thiazol-2-yl)-diaminoalkane aus α-Thiocyanato-acetophenonen und N,N′-Dialkyl-diamino-alkanen
✍ Scribed by Dr. sc. T. Zimmermann; Dr. habil. G. W. Fischer; Dr. sc. J. Teller; Prof. Dr. sc. H. Dehne; Dr. B. Olk
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 463 KB
- Volume
- 332
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Substituted N,N′‐Bis(thiazol‐2‐yl)‐diaminoalkanes from α‐Thiocyanato‐acetophenones and N,N′‐Dialkyl‐diaminoalkanes
α‐Thiocyanato‐acetophenones 1 react with N,N′‐dialkyl‐diaminoalkanes 2 in the presence of an appropriate weak acid (acetic acid, propionic acid, benzoic acid) to give the hitherto unknown N,N′‐dialkyl‐N,N′‐bis(4‐aryl‐thiazol‐2‐yl)‐diaminoalkanes 3. As reaction medium aliphatic alcohols (ethanol, methanol), halogenated hydrocarbons (methylene chloride, chloroform, carbon tetrachloride) or dipolar‐aprotic solvents (acetonitrile, dimethylformamide) can be used. ‐ I.r., u.v., n.m.r. and mass spectroscopic data of the novel bisthiazoles 3 are reported.