Substituent effects in chemical carcinogenesis: Chrysene and its methyl derivatives
β Scribed by Gregory D. Berger; Paul G. Seybold
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 418 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0020-7608
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π SIMILAR VOLUMES
## Abstract A general equation describing the effect of substituents on Ξ±βcarbons in a saturated framework was developed from ^13^C chemical shifts obtained under uniform conditions for selected aliphatic compounds. Experimental correlations for Ξ²β and Ξ³βcarbons and a discussion of the results are
## Abstract Long range interβring ^13^Cο£Ώ^13^C couplings are found to be effective in the title compounds, and the magnitudes of coupling constants and of substituent effects on ^13^C chemical shifts, as well as the signs of the latter, alternate with respect to the number of connecting bonds.
## Abstract ^13^C chemical shifts obtained under uniform conditions for selected compounds containing secondary aliphatic fragments were employed in a linear regression analysis. Twoβparameter relationships describing the substituent effects in the saturated framework were calculated, and the usefu