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Substantial expression of glycoproteins IX and V on the platelet surface from a patient with Bernard-Soulier syndrome

โœ Scribed by Morio Arai; Naomasa Yamamoto; Noriko Akamatsu; Hidenori Suzuki; Atsumi Yamaguchi; Yasuharu Nishida; Katsuyuki Fukutake; Kenjiro Tanoue


Book ID
114713691
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
313 KB
Volume
87
Category
Article
ISSN
0007-1048

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Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder due to quantitative or qualitative abnormalities in the platelet glycoprotein (GP) Ib/IX/V complex, the major von Willebrand factor receptor. The complex comprises four subunits, each encoded by a separate gene. Several mutations h