## Abstract Postโencephalitic parkinsonism is a wellโknown entity, but involvement of the basal ganglia is rarely documented. We describe a 21โyearโold man who developed parkinsonism following encephalitic illness presumed to be of viral origin with substantia nigra lesions evident on magnetic reso
Substantia nigra depigmentation and exposure to encephalitis lethargica
โ Scribed by Hack, Nawaz; Jicha, Gregory A.; Abell, Annalisa; Dean, Dawson; Vitek, Jerrold L.; Berger, Joseph R.
- Book ID
- 118751403
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 255 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
FIG. 1. MRI showed symmetric (A) hypointensity signal on T1weighted imaging and (B) hyperintensity signal on T2-weighted imaging in bilateral substantia nigra on admission. A repeated MRI after 3 months showed resolution of the lesions on (C) T2-weighted imaging and (D) T1-weighted imaging.
Posterior cortical atrophy (PCA) represents a degenerative disorder characterized by the development of higherorder visual deficit. 1 PCA may result from heterogeneous pathologies that make up tauopathies. An increasing number of mutations in the tau gene (microtubule-associated protein tau [MAPT])
## Abstract Levodopa (LD) is the most effective drug for symptomatic control of Parkinson's disease, but has been suspected to be toxic to substantia nigra (SN) dopaminergic neurons. Tissue culture and animal studies of LD toxicity have produced contradictory evidence, and one study reported that a