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Substance P Receptors in Primary Cultures of Cortical Astrocytes from the Mouse

✍ Scribed by Y. Torrens, J. C. Beaujouan, M. Saffroy, M. C. Daguet DE Montety, L. Bergström and J. Glowinski

Book ID
123633850
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
1021 KB
Volume
83
Category
Article
ISSN
0027-8424

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Mouse brain astrocytes from primary cultures were found to contain both a l and 012 adrenergic receptors. 3H WB 4101 labeled one category of binding site (KD = 1.5 f 0.39 nM, Bmax = 64 f 7.9 fmoles/mg protein) with typical 01, adrenergic specificity (WB 4101 > prazosin > yohimbine). The density of a