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Substance P-induced inflammation in the rat knee joint is mediated by neurokinin 1 (NK1) receptors

✍ Scribed by F.Y. Lam; W.R. Ferrell; D.T. Scott

Book ID
119117794
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
276 KB
Volume
46
Category
Article
ISSN
0167-0115

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Neurokinin-1 receptor (NK-1R) expression
Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P
✍ Triona Goode; Terry O'Connor; Ann Hopkins; Derek Moriarty; Gearld C. O'Sullivan; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 628 KB

## Abstract We have previously shown that the receptor for substance P (SP), neurokinin‐1 receptor (NK‐1R), is a marker of human mucosal but not peripheral mononuclear cells. In the present study, we investigate NK‐1R expression in the human colonic mucosa in vivo, particularly in the epithelial ce