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Substance P-induced cyclooxygenase-2 expression in human umbilical vein endothelial cells

✍ Scribed by Margherita Gallicchio; Arianna Carolina Rosa; Elisa Benetti; Massimo Collino; Chiara Dianzani; Roberto Fantozzi

Book ID: 110009052
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 231 KB
Volume: 147
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0706660

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## Abstract Lipopolysaccharide (LPS), as an important proinflammatory agent, targets the endothelium. However, almost all in vitro experiments of the effect of LPS on vascular endothelial cells (VECs) were performed under an artificially decreased concentration of serum that was not enough to maint